This course builds upon CHM 235, providing an in-depth exploration of organic chemistry with a focus on molecular reactivity and synthetic strategies. Topics include the chemistry of alcohols, ethers, epoxides, sulfides, conjugated and aromatic systems, carbonyl compounds, amines, carboxylic acids and their derivatives, and enol-based reactivity. The curriculum also introduces the structure and chemistry of major biomolecules, including carbohydrates, nucleic acids, amino acids, peptides, proteins, lipids, and polymers.
Concurrent enrollment in CHM 236L is required.
Prerequisites
CHM 235 with a grade of “C” or higher
1. Describe the physical properties, typical reactivity patterns, and synthetic methods associated with alcohols.
2. Describe the structural characteristics, chemical reactivity, and standard preparation techniques of ethers and epoxides.
3. Assess the key physical and chemical properties, as well as the characteristic reactions, of aldehydes and ketones.
4. Describe the structure, basicity, and chemical reactivity of amines, including their significance in pharmaceutical applications.
5. Explain the acidity, key physical properties, and prevalent chemical transformations of carboxylic acids.
6. Describe the reactivity and synthetic applications of carboxylic acid derivatives.
7. Assess the mechanisms and resulting products of alpha-substitution and carbonyl condensation reactions.
8. Explain the structural characteristics, biological functions, and practical applications of carbohydrates and nucleic acids.
9. Describe the synthesis, properties, and biological roles of amino acids, peptides, and proteins.
10. Explain the structural diversity, principal physical properties, and practical applications of lipids.
11. Describe foundational principles of polymer chemistry, focusing on polymerization mechanisms and the behavior of polymeric materials.
12. Assess the significance of molecular orbitals in conjugated pi systems and their influence on pericyclic reaction pathways.
13. Revise laboratory reports in response to feedback to enhance scientific reasoning and improve clarity.
14. Present laboratory findings effectively using clear and concise scientific writing.